Burkholderia pseudomallei K96243, BPSS1407 (bpscD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS1407
Name
bpscD
Synonym: sctD
Replicon chromosome 2
Genomic location 1920833 - 1921882 (+ strand)
CommentThis gene is part of the type III secretion system T3SS-1 locus found in B. pseudomallei but not B. mallei or B. thailandensis. B. pseudomallei T3SS-1 and T3SS-2, but not T3SS-3 contribute to pathogenicity in Solanum lycopersicum (tomato) but not human monocytic cell line THP-1. (PMID:20109238).

Cross-References

RefSeq YP_111419.1
GI 53722434
Entrez 3095934
GI 53722434
INSDC CAH38882.1
NCBI Locus Tag BPSS1407
RefSeq YP_111419.1,GeneID
UniParc UPI000043BCAA
UniProtKB Acc Q63KF3
UniProtKB ID Q63KF3_BURPS
UniRef100 UniRef100_A3NKX8
UniRef50 UniRef50_Q93KZ0
UniRef90 UniRef90_Q93KZ0

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system inner membrane ring component BpscD (T3SS-1)
Product Name Confidence: Class 2
Synonyms secretion-associated protein
Evidence for Translation
Charge (pH 7) -8.65
Kyte-Doolittle Hydrophobicity Value -0.011
Molecular Weight (kDa) 36455.5
Isoelectric Point (pI) 5.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG020890 (287 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1407
Search term: bpscD

References

PubMed ID: 20109238
PubMed ID: 28664152
PubMed ID: 21768285
PubMed ID: 10403415
PubMed ID: 11990489
PubMed ID: 15621426