Burkholderia pseudomallei K96243, BPSS1404 (bpscR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS1404
Name
bpscR
Synonym: sctR
Replicon chromosome 2
Genomic location 1918790 - 1919440 (+ strand)
CommentThis gene is part of the type III secretion system T3SS-1 locus found in B. pseudomallei but not B. mallei or B. thailandensis. B. pseudomallei T3SS-1 and T3SS-2, but not T3SS-3 contribute to pathogenicity in Solanum lycopersicum (tomato) but not human monocytic cell line THP-1. (PMID:20109238).

Cross-References

RefSeq YP_111416.1
GI 53722431
Entrez 3097269
GI 53722431
INSDC CAH38879.1
NCBI Locus Tag BPSS1404
RefSeq YP_111416.1,GeneID
UniParc UPI00000B0040
UniProtKB Acc H7C786
UniProtKB ID H7C786_BURPS
UniRef100 UniRef100_I1WTZ3
UniRef50 UniRef50_Q52488
UniRef90 UniRef90_I1WTZ3

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system inner membrane export apparatus protein BpscR (T3SS-1)
Product Name Confidence: Class 2
Synonyms type III secretion system protein
Evidence for Translation
Charge (pH 7) 0.47
Kyte-Doolittle Hydrophobicity Value 0.831
Molecular Weight (kDa) 23662.0
Isoelectric Point (pI) 7.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 325 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000026 (1240 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1404
Search term: bpscR

References

PubMed ID: 20109238
PubMed ID: 28664152
PubMed ID: 21768285
PubMed ID: 10403415
PubMed ID: 11990489
PubMed ID: 15621426