Burkholderia pseudomallei K96243, BPSS1170

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1170
Name
Replicon chromosome 2
Genomic location 1562122 - 1564590 (- strand)

Cross-References

RefSeq YP_111183.1
GI 53722198
Entrez 3095812
GI 53722198
INSDC CAH38638.1
NCBI Locus Tag BPSS1170
RefSeq YP_111183.1,GeneID
UniParc UPI000043BBC7
UniProtKB Acc Q63L38
UniProtKB ID Q63L38_BURPS
UniRef100 UniRef100_A0A088YDH8
UniRef50 UniRef50_Q3JMA8
UniRef90 UniRef90_Q3JMA8

Product

Feature Type CDS
Coding Frame 1
Product Name
non-ribosomal peptide synthase/polyketide synthase
Synonyms
Evidence for Translation
Charge (pH 7) -4.54
Kyte-Doolittle Hydrophobicity Value -0.003
Molecular Weight (kDa) 85592.4
Isoelectric Point (pI) 6.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 571 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017844 (198 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1170

Human Homologs

Ensembl 97, assembly GRCh38.p12
fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594]
E-value: 3.8e-53
Percent Identity: 31.2
Ensembl 97, assembly GRCh38.p12
fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594]
E-value: 3.8e-53
Percent Identity: 31.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268