Burkholderia pseudomallei K96243, BPSS1143

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1143
Name
Replicon chromosome 2
Genomic location 1529032 - 1530687 (- strand)

Cross-References

RefSeq YP_111156.1
GI 53722171
Entrez 3095226
GI 53722171
NCBI Locus Tag BPSS1143
RefSeq YP_111156.1,GeneID
UniProtKB Acc Q63L65
UniProtKB ID Q63L65_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
formate hydrogenlyase/hydrogenase/NADH dehydrogenase subunit
Synonyms
Evidence for Translation
Charge (pH 7) -6.88
Kyte-Doolittle Hydrophobicity Value -0.180
Molecular Weight (kDa) 59413.1
Isoelectric Point (pI) 6.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 504 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG020786 (424 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1143

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268