Burkholderia pseudomallei K96243, BPSS0839

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0839
Name
Replicon chromosome 2
Genomic location 1124884 - 1125723 (- strand)

Cross-References

RefSeq YP_110850.1
GI 53721865
Entrez 3095018
GI 53721865
INSDC CAH38301.1
NCBI Locus Tag BPSS0839
RefSeq YP_110850.1,GeneID
UniParc UPI000043BA86
UniProtKB Acc Q63M21
UniProtKB ID Q63M21_BURPS
UniRef100 UniRef100_A0A095K259
UniRef50 UniRef50_G8MA59
UniRef90 UniRef90_Q2T4Y8

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (30.4 kDa, pI 6.24, PMID:21960737)
Charge (pH 7) -4.60
Kyte-Doolittle Hydrophobicity Value -0.056
Molecular Weight (kDa) 30426.1
Isoelectric Point (pI) 6.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Unknown Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 92 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003471 (588 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0839

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268