Burkholderia pseudomallei K96243, BPSS0017

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0017
Name
Replicon chromosome 2
Genomic location 16285 - 17070 (- strand)

Cross-References

RefSeq YP_110041.1
GI 53721056
Entrez 3097141
GI 53721056
INSDC CAH37460.1
NCBI Locus Tag BPSS0017
RefSeq YP_110041.1,GeneID
UniParc UPI000043B764
UniProtKB Acc Q63PC8
UniProtKB ID Q63PC8_BURPS
UniRef100 UniRef100_A0A069B5T2
UniRef50 UniRef50_A3P2I2
UniRef90 UniRef90_A3P2I2

Product

Feature Type CDS
Coding Frame 1
Product Name
3-hydroxybutyrate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -2.11
Kyte-Doolittle Hydrophobicity Value 0.181
Molecular Weight (kDa) 27421.3
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002100 (695 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0017

Human Homologs

Ensembl 97, assembly GRCh38.p12
dehydrogenase/reductase 1 [Source:HGNC Symbol;Acc:HGNC:16445]
E-value: 1.5e-11
Percent Identity: 28.1
Ensembl 97, assembly GRCh38.p12
dehydrogenase/reductase 1 [Source:HGNC Symbol;Acc:HGNC:16445]
E-value: 1.5e-11
Percent Identity: 28.1
Ensembl 97, assembly GRCh38.p12
dehydrogenase/reductase 1 [Source:HGNC Symbol;Acc:HGNC:16445]
E-value: 1.5e-11
Percent Identity: 28.1
Ensembl 97, assembly GRCh38.p12
dehydrogenase/reductase 1 [Source:HGNC Symbol;Acc:HGNC:16445]
E-value: 1.5e-11
Percent Identity: 28.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268