Burkholderia pseudomallei K96243, BPSL3421

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3421
Name
Replicon chromosome 1
Genomic location 4063478 - 4064377 (+ strand)

Cross-References

RefSeq YP_110014.1
GI 53721028
Entrez 3094692
GI 53721028
INSDC CAH37433.1
NCBI Locus Tag BPSL3421
RefSeq YP_110014.1,GeneID
UniParc UPI000043B749
UniProtKB Acc Q63PF5
UniProtKB ID Q63PF5_BURPS
UniRef100 UniRef100_Q63PF5
UniRef50 UniRef50_A0A060P7Q0
UniRef90 UniRef90_Q63PF5

Product

Feature Type CDS
Coding Frame 1
Product Name
LysR family transcriptional regulator
Synonyms
Evidence for Translation
Charge (pH 7) 4.41
Kyte-Doolittle Hydrophobicity Value -0.077
Molecular Weight (kDa) 33323.0
Isoelectric Point (pI) 9.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 542 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000067 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3421

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268