Burkholderia pseudomallei K96243, BPSL3218 (rpsL)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL3218
Name	rpsL
Replicon	chromosome 1
Genomic location	3813544 - 3813924 (- strand)

Cross-References

RefSeq	YP_109812.1
GI	53720826
Entrez	3091469
GI	53720826
INSDC	CAH37229.1
NCBI Locus Tag	BPSL3218
RefSeq	YP_109812.1,GeneID
UniParc	UPI000043B683
UniProtKB Acc	Q63Q06
UniProtKB ID	RS12_BURPS
UniRef100	UniRef100_A3P0B8
UniRef50	UniRef50_Q8KTP6
UniRef90	UniRef90_A4SUV6

Product

Feature Type	CDS
Coding Frame	1
Product Name	30S ribosomal protein S12
Synonyms
Evidence for Translation
Charge (pH 7)	20.64
Kyte-Doolittle Hydrophobicity Value	-0.761
Molecular Weight (kDa)	13942.1
Isoelectric Point (pI)	11.53

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 659 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000253 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL3218 Search term: rpsL Search term: 30S ribosomal protein S12

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000489374 mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380] E-value: 4.2e-20 Percent Identity: 45.5
Ensembl 97, assembly GRCh38.p12	ENSP00000488926 mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380] E-value: 4.2e-20 Percent Identity: 45.5
Ensembl 97, assembly GRCh38.p12	ENSP00000489467 mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380] E-value: 4.2e-20 Percent Identity: 45.5
Ensembl 97, assembly GRCh38.p12	ENSP00000384952 mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380] E-value: 4.2e-20 Percent Identity: 45.5
Ensembl 97, assembly GRCh38.p12	ENSP00000308845 mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380] E-value: 4.2e-20 Percent Identity: 45.5
Ensembl 97, assembly GRCh38.p12	ENSP00000384579 mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380] E-value: 4.2e-20 Percent Identity: 45.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268