Burkholderia pseudomallei K96243, BPSL3210 (rplB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3210
Name
rplB
Replicon chromosome 1
Genomic location 3806375 - 3807202 (- strand)

Cross-References

RefSeq YP_109804.1
GI 53720818
Entrez 3091929
GI 53720818
INSDC CAH37221.1
NCBI Locus Tag BPSL3210
RefSeq YP_109804.1,GeneID
UniParc UPI000043B67D
UniProtKB Acc Q63Q14
UniProtKB ID RL2_BURPS
UniRef100 UniRef100_Q62GK8
UniRef50 UniRef50_Q9AMK8
UniRef90 UniRef90_Q13TH3

Product

Feature Type CDS
Coding Frame 1
Product Name
50S ribosomal protein L2
Synonyms
Evidence for Translation
Charge (pH 7) 33.57
Kyte-Doolittle Hydrophobicity Value -0.669
Molecular Weight (kDa) 30257.7
Isoelectric Point (pI) 11.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000260 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3210
Search term: rplB

Human Homologs

Ensembl 97, assembly GRCh38.p12
mitochondrial ribosomal protein L2 [Source:HGNC Symbol;Acc:HGNC:14056]
E-value: 3.7e-29
Percent Identity: 40.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268