Burkholderia pseudomallei K96243, BPSL3089

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3089
Name
Replicon chromosome 1
Genomic location 3685343 - 3687508 (+ strand)

Cross-References

RefSeq YP_109684.1
GI 53720698
Entrez 3094613
GI 53720698
INSDC CAH37100.1
NCBI Locus Tag BPSL3089
RefSeq YP_109684.1,GeneID
UniParc UPI000043B60B
UniProtKB Acc Q63QD4
UniProtKB ID Q63QD4_BURPS
UniRef100 UniRef100_Q3JN66
UniRef50 UniRef50_Q3JN66
UniRef90 UniRef90_Q3JN66

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidase
Synonyms
Evidence for Translation
Charge (pH 7) -2.22
Kyte-Doolittle Hydrophobicity Value -0.340
Molecular Weight (kDa) 79092.5
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 394 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000382 (645 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3089
Search term: peptidase

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutamyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:3355]
E-value: 1.5e-58
Percent Identity: 26.3

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268