Burkholderia pseudomallei K96243, BPSL3043 (paaG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3043
Name
paaG
Replicon chromosome 1
Genomic location 3633441 - 3634232 (+ strand)

Cross-References

RefSeq YP_109638.1
GI 53720652
Entrez 3092158
GI 53720652
INSDC CAH37054.1
NCBI Locus Tag BPSL3043
RefSeq YP_109638.1,GeneID
UniParc UPI000043B5DD
UniProtKB Acc Q63QI0
UniProtKB ID Q63QI0_BURPS
UniRef100 UniRef100_A0A097XZI5
UniRef50 UniRef50_P77467
UniRef90 UniRef90_Q2SUJ0

Product

Feature Type CDS
Coding Frame 1
Product Name
enoyl-CoA hydratase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (25.6 kDa, pI 5.24, PMID:21960737)
Charge (pH 7) -4.34
Kyte-Doolittle Hydrophobicity Value -0.035
Molecular Weight (kDa) 28399.9
Isoelectric Point (pI) 5.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 494 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000431 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3043
Search term: paaG

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268