Burkholderia pseudomallei K96243, BPSL2998 (proS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2998
Name
proS
Replicon chromosome 1
Genomic location 3573930 - 3575666 (- strand)

Cross-References

RefSeq YP_109593.1
GI 53720607
Entrez 3091660
GI 53720607
INSDC CAH37009.1
NCBI Locus Tag BPSL2998
RefSeq YP_109593.1,GeneID
UniParc UPI000043B5B1
UniProtKB Acc Q63QM5
UniProtKB ID SYP_BURPS
UniRef100 UniRef100_A3MR95
UniRef50 UniRef50_P43830
UniRef90 UniRef90_Q2SZF6

Product

Feature Type CDS
Coding Frame 1
Product Name
prolyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -10.71
Kyte-Doolittle Hydrophobicity Value -0.176
Molecular Weight (kDa) 63419.0
Isoelectric Point (pI) 5.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000475 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2998
Search term: proS

Human Homologs

Ensembl 97, assembly GRCh38.p12
prolyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:30563]
E-value: 3.1e-62
Percent Identity: 30.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268