Burkholderia pseudomallei K96243, BPSL2989

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2989
Name
Replicon chromosome 1
Genomic location 3562407 - 3562880 (+ strand)

Cross-References

RefSeq YP_109583.1
GI 53720597
Entrez 3091739
GI 53720597
INSDC CAH36999.1
NCBI Locus Tag BPSL2989
RefSeq YP_109583.1,GeneID
UniParc UPI000043B5A7
UniProtKB Acc Q63QN5
UniProtKB ID Q63QN5_BURPS
UniRef100 UniRef100_A0A069BBG8
UniRef50 UniRef50_A9AI45
UniRef90 UniRef90_A9AI45

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 4.19
Kyte-Doolittle Hydrophobicity Value 0.275
Molecular Weight (kDa) 15362.3
Isoelectric Point (pI) 11.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Outer Membrane Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 88 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000486 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2989
Search term: lipoprotein

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268