Burkholderia pseudomallei K96243, BPSL2941 (dapB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2941
Name
dapB
Replicon chromosome 1
Genomic location 3512355 - 3513161 (- strand)

Cross-References

RefSeq YP_109535.1
GI 53720549
Entrez 3094347
GI 53720549
INSDC CAH36951.1
NCBI Locus Tag BPSL2941
RefSeq YP_109535.1,GeneID
UniParc UPI000043B578
UniProtKB Acc Q63QT3
UniProtKB ID DAPB_BURPS
UniRef100 UniRef100_Q3JNM7
UniRef50 UniRef50_Q1C0I8
UniRef90 UniRef90_Q2SZ94

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrodipicolinate reductase
Synonyms
Evidence for Translation
Charge (pH 7) -1.90
Kyte-Doolittle Hydrophobicity Value 0.076
Molecular Weight (kDa) 28135.8
Isoelectric Point (pI) 6.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4F3Y OXIDOREDUCTASE 05/09/12 X-Ray Crystal Structure of Dihydrodipicolinate reductase from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 2.1 X-RAY DIFFRACTION 97.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000530 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2941
Search term: dapB

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268