Burkholderia pseudomallei K96243, BPSL2928 (purB)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL2928
Name	purB
Replicon	chromosome 1
Genomic location	3496763 - 3498214 (+ strand)

Cross-References

RefSeq	YP_109522.1
GI	53720536
Entrez	3093830
GI	53720536
INSDC	CAH36938.1
NCBI Locus Tag	BPSL2928
RefSeq	YP_109522.1,GeneID
UniParc	UPI000043B56B
UniProtKB Acc	Q63QU6
UniProtKB ID	Q63QU6_BURPS
UniRef100	UniRef100_A0A069BAX9
UniRef50	UniRef50_P0AB90
UniRef90	UniRef90_Q2SZ81

Product

Feature Type	CDS
Coding Frame	1
Product Name	adenylosuccinate lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.19
Kyte-Doolittle Hydrophobicity Value	-0.204
Molecular Weight (kDa)	54192.4
Isoelectric Point (pI)	6.73

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268 Extracellular Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 593 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000545 (653 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL2928 Search term: purB Search term: adenylosuccinate lyase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268