Burkholderia pseudomallei K96243, BPSL2872 (secF)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL2872
Name	secF
Replicon	chromosome 1
Genomic location	3437518 - 3438468 (+ strand)

Cross-References

RefSeq	YP_109466.1
GI	53720480
Entrez	3092984
GI	53720480
INSDC	CAH36882.1
NCBI Locus Tag	BPSL2872
RefSeq	YP_109466.1,GeneID
UniParc	UPI000043B533
UniProtKB Acc	Q63R02
UniProtKB ID	Q63R02_BURPS
UniRef100	UniRef100_A0A069B448
UniRef50	UniRef50_Q5FA42
UniRef90	UniRef90_Q2SZ27

Product

Feature Type	CDS
Coding Frame	1
Product Name	preprotein translocase subunit SecF
Synonyms
Evidence for Translation
Charge (pH 7)	2.89
Kyte-Doolittle Hydrophobicity Value	0.468
Molecular Weight (kDa)	35136.8
Isoelectric Point (pI)	8.45

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000592 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL2872 Search term: secF Search term: preprotein translocase subunit SecF

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268