Burkholderia pseudomallei K96243, BPSL2439 (acpP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2439
Name
acpP
Replicon chromosome 1
Genomic location 2944967 - 2945206 (- strand)

Cross-References

RefSeq YP_109031.1
GI 53720045
Entrez 3092505
GI 53720045
INSDC CAH36442.1
NCBI Locus Tag BPSL2439
RefSeq YP_109031.1,GeneID
UniParc UPI00003A5F84
UniProtKB Acc Q63S86
UniProtKB ID ACP_BURPS
UniRef100 UniRef100_Q1BXV1
UniRef50 UniRef50_Q8Y0J1
UniRef90 UniRef90_Q8Y0J1

Product

Feature Type CDS
Coding Frame 1
Product Name
acyl carrier protein
Synonyms
Evidence for Translation
Charge (pH 7) -12.01
Kyte-Doolittle Hydrophobicity Value -0.254
Molecular Weight (kDa) 8711.7
Isoelectric Point (pI) 3.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 574 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000965 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2439
Search term: acpP

Human Homologs

Ensembl 97, assembly GRCh38.p12
NADH:ubiquinone oxidoreductase subunit AB1 [Source:HGNC Symbol;Acc:HGNC:7694]
E-value: 9.3e-10
Percent Identity: 53.8

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268