Burkholderia pseudomallei K96243, BPSL2403 (plcN)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL2403
Name	plcN
Replicon	chromosome 1
Genomic location	2902870 - 2904972 (+ strand)

Cross-References

RefSeq	YP_108995.1
GI	53720009
Entrez	3093316
GI	53720009
INSDC	CAH36406.1
NCBI Locus Tag	BPSL2403
RefSeq	YP_108995.1,GeneID
UniParc	UPI000043B382
UniProtKB Acc	Q9RGS8
UniProtKB ID	PHLN_BURPS
UniRef100	UniRef100_Q9RGS8
UniRef50	UniRef50_Q9RGS8
UniRef90	UniRef90_Q9RGS8

Product

Feature Type	CDS
Coding Frame	1
Product Name	non-hemolytic phospholipase C
Synonyms
Evidence for Translation
Charge (pH 7)	-2.57
Kyte-Doolittle Hydrophobicity Value	-0.396
Molecular Weight (kDa)	77076.4
Isoelectric Point (pI)	6.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 1 quantitative mass spectrometry evidence 25635268 Extracellular Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 99 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001009 (1747 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL2403 Search term: plcN Search term: non-hemolytic phospholipase C

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268