Burkholderia pseudomallei K96243, BPSL2239 (ask)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL2239
Name	ask
Replicon	chromosome 1
Genomic location	2700393 - 2701643 (- strand)

Cross-References

RefSeq	YP_108834.1
GI	53719848
Entrez	3094028
GI	53719848
INSDC	CAH36241.1
NCBI Locus Tag	BPSL2239
RefSeq	YP_108834.1,GeneID
UniParc	UPI000043B2E1
UniProtKB Acc	Q63ST2
UniProtKB ID	Q63ST2_BURPS
UniRef100	UniRef100_A0A069B901
UniRef50	UniRef50_Q1LPF1
UniRef90	UniRef90_Q13X64

Product

Feature Type	CDS
Coding Frame	1
Product Name	aspartate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-14.08
Kyte-Doolittle Hydrophobicity Value	-0.067
Molecular Weight (kDa)	45141.2
Isoelectric Point (pI)	4.81

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 639 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001966 (653 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL2239 Search term: ask Search term: aspartate kinase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268