Burkholderia pseudomallei K96243, BPSL2235

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2235
Name
Replicon chromosome 1
Genomic location 2691571 - 2694717 (+ strand)

Cross-References

RefSeq YP_108830.1
GI 53719844
Entrez 3093296
GI 53719844
INSDC CAH36237.1
NCBI Locus Tag BPSL2235
RefSeq YP_108830.1,GeneID
UniParc UPI000043B2DD
UniProtKB Acc Q63ST6
UniProtKB ID Q63ST6_BURPS
UniRef100 UniRef100_Q63ST6
UniRef50 UniRef50_A0A085UAG0
UniRef90 UniRef90_A1V5F5

Product

Feature Type CDS
Coding Frame 1
Product Name
AcrB/AcrD/AcrF family membrane protein
Synonyms
Evidence for Translation
Charge (pH 7) 9.48
Kyte-Doolittle Hydrophobicity Value 0.370
Molecular Weight (kDa) 112381.4
Isoelectric Point (pI) 8.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG021019 (305 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2235

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268