Burkholderia pseudomallei K96243, BPSL2140 (ppsA)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL2140
Name	ppsA
Replicon	chromosome 1
Genomic location	2566768 - 2569167 (- strand)

Cross-References

RefSeq	YP_108735.1
GI	53719749
Entrez	3092220
GI	53719749
INSDC	CAH36142.1
NCBI Locus Tag	BPSL2140
RefSeq	YP_108735.1,GeneID
UniParc	UPI000043B27F
UniProtKB Acc	Q63T31
UniProtKB ID	Q63T31_BURPS
UniRef100	UniRef100_A3NAS6
UniRef50	UniRef50_P23538
UniRef90	UniRef90_Q2SWX9

Product

Feature Type	CDS
Coding Frame	1
Product Name	phosphoenolpyruvate synthase
Synonyms
Evidence for Translation
Charge (pH 7)	-18.02
Kyte-Doolittle Hydrophobicity Value	-0.181
Molecular Weight (kDa)	87768.4
Isoelectric Point (pI)	5.10

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543 Extracellular Class 1 quantitative mass spectrometry evidence 25635268
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 623 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001892 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL2140 Search term: ppsA Search term: phosphoenolpyruvate synthase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268