Burkholderia pseudomallei K96243, BPSL2080

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2080
Name
Replicon chromosome 1
Genomic location 2497797 - 2500589 (+ strand)

Cross-References

RefSeq YP_108679.1
GI 53719693
Entrez 3091924
GI 53719693
INSDC CAH36081.1
NCBI Locus Tag BPSL2080
RefSeq YP_108679.1,GeneID
UniParc UPI000043B248
UniProtKB Acc Q63T87
UniProtKB ID Q63T87_BURPS
UniRef100 UniRef100_Q63T87
UniRef50 UniRef50_Q3JTG9
UniRef90 UniRef90_Q3JTG9

Product

Feature Type CDS
Coding Frame 1
Product Name
glycosyl hydrolase
Synonyms
Evidence for Translation
Charge (pH 7) 21.73
Kyte-Doolittle Hydrophobicity Value -0.134
Molecular Weight (kDa) 100866.3
Isoelectric Point (pI) 9.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG015641 (581 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2080

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268