Burkholderia pseudomallei K96243, BPSL1552

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1552
Name
Replicon chromosome 1
Genomic location 1801377 - 1802021 (+ strand)

Cross-References

RefSeq YP_108172.1
GI 53719186
Entrez 3093192
GI 53719186
INSDC CAH35553.1
NCBI Locus Tag BPSL1552
RefSeq YP_108172.1,GeneID
UniParc UPI000043B051
UniProtKB Acc Q63UP4
UniProtKB ID Q63UP4_BURPS
UniRef100 UniRef100_A1V4F7
UniRef50 UniRef50_Q7NQN4
UniRef90 UniRef90_Q2SWA5

Product

Feature Type CDS
Coding Frame 1
Product Name
outer membrane protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 3.60
Kyte-Doolittle Hydrophobicity Value 0.186
Molecular Weight (kDa) 22763.1
Isoelectric Point (pI) 8.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 149 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001589 (649 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1552

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268