Burkholderia pseudomallei K96243, BPSL1542

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1542
Name
Replicon chromosome 1
Genomic location 1786752 - 1787936 (+ strand)

Cross-References

RefSeq YP_108162.1
GI 53719176
Entrez 3092176
GI 53719176
INSDC CAH35543.1
NCBI Locus Tag BPSL1542
RefSeq YP_108162.1,GeneID
UniParc UPI000043B047
UniProtKB Acc Q63UQ4
UniProtKB ID Q63UQ4_BURPS
UniRef100 UniRef100_Q3JRT5
UniRef50 UniRef50_Q0KBN9
UniRef90 UniRef90_Q3JRT5

Product

Feature Type CDS
Coding Frame 1
Product Name
cystathionine beta-lyase
Synonyms
Evidence for Translation
Charge (pH 7) -4.19
Kyte-Doolittle Hydrophobicity Value 0.024
Molecular Weight (kDa) 42779.4
Isoelectric Point (pI) 6.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001618 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1542

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268