Burkholderia pseudomallei K96243, BPSL1484 (clpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1484
Name
clpB
Replicon chromosome 1
Genomic location 1720727 - 1723357 (+ strand)

Cross-References

RefSeq YP_108104.1
GI 53719118
Entrez 3094211
GI 53719118
NCBI Locus Tag BPSL1484
RefSeq YP_108104.1,GeneID
UniProtKB Acc Q63UW2
UniProtKB ID Q63UW2_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
ClpB heat-shock protein
Synonyms
Evidence for Translation
Charge (pH 7) -14.39
Kyte-Doolittle Hydrophobicity Value -0.336
Molecular Weight (kDa) 97277.3
Isoelectric Point (pI) 5.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001681 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1484
Search term: clpB

Human Homologs

Ensembl 97, assembly GRCh38.p12
ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]
E-value: 2.3e-48
Percent Identity: 35.2
Ensembl 97, assembly GRCh38.p12
ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]
E-value: 2.3e-48
Percent Identity: 35.2
Ensembl 97, assembly GRCh38.p12
ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]
E-value: 2.3e-48
Percent Identity: 35.2
Ensembl 97, assembly GRCh38.p12
ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]
E-value: 2.3e-48
Percent Identity: 35.2
Ensembl 97, assembly GRCh38.p12
ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]
E-value: 2.3e-48
Percent Identity: 35.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268