Burkholderia pseudomallei K96243, BPSL1477 (hom)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1477
Name
hom
Replicon chromosome 1
Genomic location 1713350 - 1714678 (+ strand)

Cross-References

RefSeq YP_108097.1
GI 53719111
Entrez 3094454
GI 53719111
INSDC CAH35478.1
NCBI Locus Tag BPSL1477
RefSeq YP_108097.1,GeneID
UniParc UPI000043B007
UniProtKB Acc Q63UW9
UniProtKB ID Q63UW9_BURPS
UniRef100 UniRef100_A0A069B8C2
UniRef50 UniRef50_P29365
UniRef90 UniRef90_B4EB12

Product

Feature Type CDS
Coding Frame 1
Product Name
homoserine dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -6.81
Kyte-Doolittle Hydrophobicity Value 0.125
Molecular Weight (kDa) 47002.4
Isoelectric Point (pI) 5.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001688 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1477
Search term: hom

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268