Burkholderia pseudomallei K96243, BPSL1413 (pgi)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1413
Name
pgi
Replicon chromosome 1
Genomic location 1644934 - 1646556 (- strand)

Cross-References

RefSeq YP_108035.1
GI 53719049
Entrez 3093521
GI 53719049
INSDC CAH35415.1
NCBI Locus Tag BPSL1413
RefSeq YP_108035.1,GeneID
UniParc UPI000043AFC9
UniProtKB Acc Q63V31
UniProtKB ID G6PI_BURPS
UniRef100 UniRef100_Q3JRE2
UniRef50 UniRef50_Q39FF4
UniRef90 UniRef90_Q3JRE2

Product

Feature Type CDS
Coding Frame 1
Product Name
glucose-6-phosphate isomerase
Synonyms
Evidence for Translation
Charge (pH 7) -4.47
Kyte-Doolittle Hydrophobicity Value -0.045
Molecular Weight (kDa) 58812.5
Isoelectric Point (pI) 6.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 534 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001781 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1413
Search term: pgi

Human Homologs

Ensembl 97, assembly GRCh38.p12
glucose-6-phosphate isomerase [Source:HGNC Symbol;Acc:HGNC:4458]
E-value: 1.6e-140
Percent Identity: 49.0
Ensembl 97, assembly GRCh38.p12
glucose-6-phosphate isomerase [Source:HGNC Symbol;Acc:HGNC:4458]
E-value: 1.6e-140
Percent Identity: 49.0

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268