Burkholderia pseudomallei K96243, BPSL1207 (pnp)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1207
Name
pnp
Replicon chromosome 1
Genomic location 1391849 - 1393990 (+ strand)

Cross-References

RefSeq YP_107829.1
GI 53718843
Entrez 3092633
GI 53718843
INSDC CAH35202.1
NCBI Locus Tag BPSL1207
RefSeq YP_107829.1,GeneID
UniParc UPI000043AEFB
UniProtKB Acc Q63VN7
UniProtKB ID PNP_BURPS
UniRef100 UniRef100_A3NTA2
UniRef50 UniRef50_P41121
UniRef90 UniRef90_Q142H7

Product

Feature Type CDS
Coding Frame 1
Product Name
polynucleotide phosphorylase
Synonyms
Evidence for Translation
Charge (pH 7) -15.90
Kyte-Doolittle Hydrophobicity Value -0.117
Molecular Weight (kDa) 76989.5
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002140 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1207
Search term: pnp

Human Homologs

Ensembl 97, assembly GRCh38.p12
polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166]
E-value: 9.9e-119
Percent Identity: 37.8
Ensembl 97, assembly GRCh38.p12
polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166]
E-value: 9.9e-119
Percent Identity: 37.8

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268