Burkholderia pseudomallei K96243, BPSL1054 (eco)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1054
Name
eco
Replicon chromosome 1
Genomic location 1222077 - 1222616 (+ strand)

Cross-References

RefSeq YP_107679.1
GI 53718693
Entrez 3094320
GI 53718693
INSDC CAH35049.1
NCBI Locus Tag BPSL1054
RefSeq YP_107679.1,GeneID
UniParc UPI000043AE65
UniProtKB Acc Q63W37
UniProtKB ID Q63W37_BURPS
UniRef100 UniRef100_Q63W37
UniRef50 UniRef50_Q9I088
UniRef90 UniRef90_B1HEK9

Product

Feature Type CDS
Coding Frame 1
Product Name
ecotin
Synonyms
Evidence for Translation
Charge (pH 7) 2.41
Kyte-Doolittle Hydrophobicity Value -0.084
Molecular Weight (kDa) 19425.0
Isoelectric Point (pI) 8.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 38 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002258 (629 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1054
Search term: eco
Search term: ecotin

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268