Burkholderia pseudomallei K96243, BPSL0776 (recA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0776
Name
recA
Replicon chromosome 1
Genomic location 903338 - 904408 (+ strand)

Cross-References

RefSeq YP_107401.1
GI 53718415
Entrez 3094325
GI 53718415
INSDC CAH34768.1
NCBI Locus Tag BPSL0776
RefSeq YP_107401.1,GeneID
UniParc UPI000042AFFF
UniProtKB Acc Q66X92
UniProtKB ID RECA_BURPS
UniRef100 UniRef100_Q62MH0
UniRef50 UniRef50_A9AFT0
UniRef90 UniRef90_A9AFT0

Product

Feature Type CDS
Coding Frame 1
Product Name
recombinase A
Synonyms
Evidence for Translation
Charge (pH 7) -8.77
Kyte-Doolittle Hydrophobicity Value -0.122
Molecular Weight (kDa) 38172.4
Isoelectric Point (pI) 4.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database Victors : 2014
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Mus musculus
Notes recA mutant is attenuated in mice
Reference 16997946

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002510 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0776
Search term: recA
Search term: recombinase A

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268