Burkholderia pseudomallei K96243, BPSL0734

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0734
Name
Replicon chromosome 1
Genomic location 847843 - 848805 (- strand)

Cross-References

RefSeq YP_107360.1
GI 53718374
Entrez 3094440
GI 53718374
NCBI Locus Tag BPSL0734
RefSeq YP_107360.1,GeneID
UniProtKB Acc Q63X06
UniProtKB ID Q63X06_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component transcriptional response regulator
Synonyms
Evidence for Translation
Charge (pH 7) -9.12
Kyte-Doolittle Hydrophobicity Value -0.183
Molecular Weight (kDa) 35376.6
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 41 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004548 (608 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0734

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268