Burkholderia pseudomallei K96243, BPSL0204 (hslV)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0204
Name
hslV
Replicon chromosome 1
Genomic location 212283 - 212819 (- strand)

Cross-References

RefSeq YP_106832.1
GI 53717846
Entrez 3091995
GI 53717846
INSDC CAH34191.1
NCBI Locus Tag BPSL0204
RefSeq YP_106832.1,GeneID
UniParc UPI000043AB1F
UniProtKB Acc Q63YI3
UniProtKB ID HSLV_BURPS
UniRef100 UniRef100_Q62EZ9
UniRef50 UniRef50_Q6CZ92
UniRef90 UniRef90_B2JJX8

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-dependent protease peptidase subunit
Synonyms
Evidence for Translation
Charge (pH 7) -0.35
Kyte-Doolittle Hydrophobicity Value -0.087
Molecular Weight (kDa) 19052.5
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 364 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002914 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0204
Search term: hslV

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268