Burkholderia ambifaria AMMD, BAMB_RS28745 (hmqE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia ambifaria AMMD - Assembly GCF_000203915.1
GCF_000203915.1|latest |
| Locus Tag |
BAMB_RS28745
|
| NCBI Old Locus Tag | Bamb_5767 |
| Name |
hmqE
|
| Replicon | chromosome 3 |
| Genomic location | 231871 - 232767 (+ strand) |
| Comment | Belongs to the HMAQ biosynthesis operon hmqABCDEFG |
Cross-References
| RefSeq | WP_011660665.1 |
| GI | 499979947 |
| NCBI Locus Tag | BAMB_RS28745 |
| NCBI Old Locus Tag | Bamb_5767 |
| RefSeq | WP_011660665.1 |
Product
| Feature Type | CDS |
| Coding Frame | NA |
| Product Name |
MBL fold metallo-hydrolase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -5.07 |
| Kyte-Doolittle Hydrophobicity Value | -0.109 |
| Molecular Weight (kDa) | 33445.7 |
| Isoelectric Point (pI) | 6.45 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG017409 (462 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BAMB_RS28745
Search term: hmqE
Search term: MBL fold metallo-hydrolase
|
Human Homologs
References
|
Burkholderia pseudomallei, B. thailandensis, and B. ambifaria produce 4-hydroxy-2-alkylquinoline analogues with a methyl group at the 3 position that is required for quorum-sensing regulation.
Vial L, Lépine F, Milot S, Groleau MC, Dekimpe V, Woods DE, Déziel E
J Bacteriol 2008 Aug;190(15):5339-52
PubMed ID: 18539738
|
|
Interplay between 4-Hydroxy-3-Methyl-2-Alkylquinoline and <i>N</i>-Acyl-Homoserine Lactone Signaling in a <i>Burkholderia cepacia</i> Complex Clinical Strain.
Chapalain A, Groleau MC, Le Guillouzer S, Miomandre A, Vial L, Milot S, Déziel E
Front Microbiol 2017;8:1021
PubMed ID: 28676791
|