Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS03200 (pagL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS03200
NCBI Old Locus TagBURCENK562V_C0430
Name
pagL
Replicon ctg7180000002936
Genomic location 306380 - 306949 (- strand)

Cross-References

RefSeq WP_006483740.1
GI 493529725
GI 493529725
NCBI Locus Tag BURCENK562V_RS03200
NCBI Old Locus Tag BURCENK562V_C0430
RefSeq WP_006483740.1

Product

Feature Type CDS
Coding Frame 1
Product Name
Lipid A deacylase PagL
Product Name Confidence: Class 2
Synonyms deacylase
Evidence for Translation
Charge (pH 7) 6.15
Kyte-Doolittle Hydrophobicity Value -0.273
Molecular Weight (kDa) 20869.4
Isoelectric Point (pI) 10.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002665 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: pagL

Human Homologs

References

The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia.
Fathy Mohamed Y, Hamad M, Ortega XP, Valvano MA
Mol Microbiol 2017 Apr;104(1):144-162
PubMed ID: 28085228