Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS18915 (amiI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
BURCENK562V_RS18915
NCBI Old Locus TagBURCENK562V_C5374
Name
amiI
Replicon ctg7180000002940B
Genomic location 2949208 - 2950623 (+ strand)

Cross-References

RefSeq WP_006491536.1
GI 493537625
GI 493537625
NCBI Locus Tag BURCENK562V_RS18915
NCBI Old Locus Tag BURCENK562V_C5374
RefSeq WP_006491536.1

Product

Feature Type CDS
Coding Frame 1
Product Name
amidase
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -5.89
Kyte-Doolittle Hydrophobicity Value 0.103
Molecular Weight (kDa) 49895.7
Isoelectric Point (pI) 6.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database BGD
Category amidase
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Rattus norvegicus
Notes amiI mutant has reduced rate of persistence in agar bead model of chronic lung infection
Reference 14977960

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002518 (1238 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: amiI
Search term: amidase

References

The Burkholderia cepacia epidemic strain marker is part of a novel genomic island encoding both virulence and metabolism-associated genes in Burkholderia cenocepacia.
Baldwin A, Sokol PA, Parkhill J, Mahenthiralingam E.
Infect Immun. 2004 Mar;72(3):1537-47.
PubMed ID: 14977960