Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS22195 (arnC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS22195
|
| NCBI Old Locus Tag | BURCENK562V_C1271 |
| Name |
arnC
|
| Replicon | ctg7180000002937 |
| Genomic location | 431999 - 433036 (- strand) |
| Comment | In PMID:27597847: arnT, arnB, arnC, arnA1, arnA2 and BURCENK562V_RS22180 ortholog BCAL1935 located in the arn gene cluster harbored significantly low frequencies of transposon insertions (TraDIS). They were therefore categorized as essential by the authors. |
Cross-References
| RefSeq | WP_006482860.1 |
| GI | 493528843 |
| EC Number | 2.4.-.- |
| GI | 493528843 |
| NCBI Locus Tag | BURCENK562V_RS22195 |
| NCBI Old Locus Tag | BURCENK562V_C1271 |
| RefSeq | WP_006482860.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 1.62 |
| Kyte-Doolittle Hydrophobicity Value | 0.113 |
| Molecular Weight (kDa) | 38426.0 |
| Isoelectric Point (pI) | 7.69 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG001694 (652 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS22195
Search term: arnC
|
Human Homologs
References
|
PubMed ID: 22742453
|
|
A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability.
Ortega XP, Cardona ST, Brown AR, Loutet SA, Flannagan RS, Campopiano DJ, Govan JR, Valvano MA
J Bacteriol 2007 May;189(9):3639-44
PubMed ID: 17337576
|
|
Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS.
Wong YC, Abd El Ghany M, Naeem R, Lee KW, Tan YC, Pain A, Nathan S
Front Microbiol 2016;7:1288
PubMed ID: 27597847
|