Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
Locus Tag |
BURCENK562V_RS24215
|
NCBI Old Locus Tag | BURCENK562V_C1709 |
Name |
rpoN
|
Replicon | ctg7180000002938 |
Genomic location | 412568 - 413959 (- strand) |
RefSeq | WP_006483492.1 |
GI | 493529477 |
GI | 493529477 |
NCBI Locus Tag | BURCENK562V_RS24215 |
NCBI Old Locus Tag | BURCENK562V_C1709 |
RefSeq | WP_006483492.1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
alternative sigma factor RpoN
|
Synonyms |
Fis family transcriptional regulator |
Evidence for Translation | |
Charge (pH 7) | -10.21 |
Kyte-Doolittle Hydrophobicity Value | -0.155 |
Molecular Weight (kDa) | 51487.1 |
Isoelectric Point (pI) | 5.51 |
Individual Mappings | |
Additional evidence for subcellular localization |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Source 1 | |
Database | BGD |
Category | Alternative Sigma factors |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | rpoN mutant cannot delay phagolysosomal fusion in mouse RAW 264.7 macrophages |
Reference | 18195023 |
Source 2 | |
Database | BGD |
Category | Alternative Sigma factors |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | rpoN mutant attenuated for virulence in agar bead model of chronic lung infection |
Reference | 15213146 |
Burkholderia Ortholog Group |
BG001356 (648 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS24215
Search term: rpoN
Search term: alternative sigma factor RpoN
|
Identification of Burkholderia cenocepacia genes required for bacterial survival in vivo.
Hunt TA, Kooi C, Sokol PA, Valvano MA
Infect Immun 2004 Jul;72(7):4010-22
PubMed ID: 15213146
|
Burkholderia cenocepacia requires the RpoN sigma factor for biofilm formation and intracellular trafficking within macrophages.
Saldías MS, Lamothe J, Wu R, Valvano MA
Infect Immun 2008 Mar;76(3):1059-67
PubMed ID: 18195023
|