Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS28565 (paaF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
BURCENK562V_RS28565
NCBI Old Locus TagBURCENK562V_C6719
Name
paaF
Replicon ctg7180000002941
Genomic location 520770 - 521546 (+ strand)

Cross-References

RefSeq WP_006491102.1
GI 493537172
GI 493537172
NCBI Locus Tag BURCENK562V_RS28565
NCBI Old Locus Tag BURCENK562V_C6719
RefSeq WP_006491102.1

Product

Feature Type CDS
Coding Frame 1
Product Name
enoyl-CoA hydratase
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -3.37
Kyte-Doolittle Hydrophobicity Value 0.074
Molecular Weight (kDa) 27995.1
Isoelectric Point (pI) 5.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000434 (681 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: paaF

Human Homologs

Ensembl 83, assembly GRCh38
enoyl CoA hydratase, short chain, 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:3151]
E-value: 1.3e-75
Percent Identity: 56.4

References

A functional phenylacetic acid catabolic pathway is required for full pathogenicity of Burkholderia cenocepacia in the Caenorhabditis elegans host model.
Law RJ(1), Hamlin JN, Sivro A, McCorrister SJ, Cardama GA, Cardona ST.
J Bacteriol. 2008 Nov;190(21):7209-18.
PubMed ID: 18776009