Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS27075 (msbA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS27075
|
| NCBI Old Locus Tag | BURCENK562V_C6402 |
| Name |
msbA
|
| Replicon | ctg7180000002941 |
| Genomic location | 226150 - 227937 (+ strand) |
Cross-References
| RefSeq | WP_012492746.1 |
| GI | 501469301 |
| EC Number | 3.6.3.- |
| GI | 501469301 |
| NCBI Locus Tag | BURCENK562V_RS27075 |
| NCBI Old Locus Tag | BURCENK562V_C6402 |
| RefSeq | WP_012492746.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
ATP-binding protein
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 7.39 |
| Kyte-Doolittle Hydrophobicity Value | 0.254 |
| Molecular Weight (kDa) | 64915.0 |
| Isoelectric Point (pI) | 9.40 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG002193 (654 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS27075
Search term: msbA
Search term: ATP-binding protein
|
Human Homologs
|
Ensembl
97, assembly
GRCh38.p12
|
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value:
5.1e-68
Percent Identity:
40.1
|
|
Ensembl
97, assembly
GRCh38.p12
|
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value:
5.1e-68
Percent Identity:
40.1
|
References
|
The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia.
Fathy Mohamed Y, Hamad M, Ortega XP, Valvano MA
Mol Microbiol 2017 Apr;104(1):144-162
PubMed ID: 28085228
|
|
Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter.
Polissi A, Georgopoulos C
Mol Microbiol 1996 Jun;20(6):1221-33
PubMed ID: 8809774
|