Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS30450 (rpoE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
BURCENK562V_RS30450
NCBI Old Locus TagBURCENK562V_C6036
Name
rpoE
Replicon ctg7180000002940C
Genomic location 370532 - 371131 (+ strand)

Cross-References

RefSeq WP_006490873.1
GI 493536937
GI 493536937
NCBI Locus Tag BURCENK562V_RS30450
NCBI Old Locus Tag BURCENK562V_C6036
RefSeq WP_006490873.1

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma factor RpoE
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -2.79
Kyte-Doolittle Hydrophobicity Value -0.372
Molecular Weight (kDa) 22593.5
Isoelectric Point (pI) 5.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database BGD
Category Alternative Sigma factors
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Mus musculus
Notes rpoE mutant cannot delay phagolysosomal fusion in mouse RAW 264.7 macrophages
Reference 18227267

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000968 (679 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: rpoE

References

Burkholderia cenocepacia requires RpoE for growth under stress conditions and delay of phagolysosomal fusion in macrophages.
Flannagan RS, Valvano MA.
Microbiology. 2008 Feb;154(Pt 2):643-53.
PubMed ID: 18227267