Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS29055 (rmlA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS29055
|
| NCBI Old Locus Tag | BURCENK562V_C5742 |
| Name |
rmlA
|
| Replicon | ctg7180000002940C |
| Genomic location | 98920 - 99813 (+ strand) |
Cross-References
| RefSeq | WP_006485115.1 |
| GI | 493531112 |
| EC Number | 2.7.7.24 |
| GI | 493531112 |
| NCBI Locus Tag | BURCENK562V_RS29055 |
| NCBI Old Locus Tag | BURCENK562V_C5742 |
| RefSeq | WP_006485115.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
glucose-1-phosphate thymidylyltransferase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -4.45 |
| Kyte-Doolittle Hydrophobicity Value | -0.102 |
| Molecular Weight (kDa) | 32856.3 |
| Isoelectric Point (pI) | 5.90 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6N0U | TRANSFERASE | 11/07/18 | Crystal structure of a glucose-1-phosphate thymidylyltransferase from Burkholderia phymatum bound to 2'-deoxy-thymidine-B-L-rhamnose | PARABURKHOLDERIA PHYMATUM (STRAIN DSM 17167 / CIP 108236 / LMG 21445 / STM815) | 2.1 | X-RAY DIFFRACTION | 90.5 |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG000731 (658 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS29055
Search term: rmlA
Search term: glucose-1-phosphate thymidylyltransferase
|
Human Homologs
|
Ensembl
97, assembly
GRCh38.p12
|
eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]
E-value:
1.1e-05
Percent Identity:
37.5
|
|
Ensembl
97, assembly
GRCh38.p12
|
eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]
E-value:
1.1e-05
Percent Identity:
37.5
|
|
Ensembl
97, assembly
GRCh38.p12
|
eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]
E-value:
1.1e-05
Percent Identity:
37.5
|
|
Ensembl
97, assembly
GRCh38.p12
|
eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]
E-value:
1.1e-05
Percent Identity:
37.5
|
References
|
A new route to dTDP-6-deoxy-l-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis.
Yoo HG, Kwon SY, Karki S, Kwon HJ
Bioorg Med Chem Lett 2011 Jul 1;21(13):3914-7
PubMed ID: 21640586
|