Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS33010 (shvR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS33010
NCBI Old Locus TagBURCENK562V_C7335
Name
shvR
Replicon ctg7180000002943
Genomic location 460263 - 461255 (- strand)

Cross-References

RefSeq WP_020980030.1
GI 537745774
GI 537745774
NCBI Locus Tag BURCENK562V_RS33010
NCBI Old Locus Tag BURCENK562V_C7335
RefSeq WP_020980030.1

Product

Feature Type CDS
Coding Frame 1
Product Name
ShvR
Product Name Confidence: Class 1
Synonyms LysR substrate-binding domain protein
Evidence for Translation
Charge (pH 7) 2.46
Kyte-Doolittle Hydrophobicity Value -0.050
Molecular Weight (kDa) 36409.3
Isoelectric Point (pI) 7.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database BGD
Category ShvR regulator
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Medicago sativa
Notes shvR is avirulent in alfalfa seedling model of infection.
Reference 17967860

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005276 (86 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: shvR
Search term: ShvR

Human Homologs

References

A LysR-type transcriptional regulator in Burkholderia cenocepacia influences colony morphology and virulence.
Bernier SP, Nguyen DT, Sokol PA
Infect Immun 2008 Jan;76(1):38-47
PubMed ID: 17967860