Burkholderia cenocepacia J2315, BCAM2298

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2298
NCBI Locus Tag	QU43_RS65865
Name
Replicon	chromosome 2
Genomic location	2579156 - 2580667 (- strand)

Cross-References

RefSeq	YP_002234897.1
GI	206564134
Entrez	6929873
GI	206564134
NCBI Locus Tag	QU43_RS65865
NCBI Old Locus Tag	BCAM2298
RefSeq	YP_002234897.1
UniProtKB Acc	B4EH14
UniProtKB ID	B4EH14_BURCJ

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative phenylacetaldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-9.93
Kyte-Doolittle Hydrophobicity Value	0.087
Molecular Weight (kDa)	53434.7
Isoelectric Point (pI)	4.92

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4O5H	OXIDOREDUCTASE	12/19/13	X-ray crystal structure of a putative phenylacetaldehyde dehydrogenase from Burkholderia cenocepacia	BURKHOLDERIA CENOCEPACIA	2.0	X-RAY DIFFRACTION	99.8

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 597 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003755 (1074 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2298 Search term: putative phenylacetaldehyde dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000438296 aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472] E-value: 4.0e-122 Percent Identity: 47.3

References