Burkholderia cenocepacia J2315, BCAM2187 (macB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2187
NCBI Locus TagQU43_RS65300
Name
macB
Replicon chromosome 2
Genomic location 2443695 - 2445740 (+ strand)

Cross-References

RefSeq WP_006483164.1
GI 206564024
Entrez 6929776
GI 206564024
INSDC CAR56045.1
NCBI Locus Tag QU43_RS65300
NCBI Old Locus Tag BCAM2187
RefSeq WP_006483164.1,GeneID
UniParc UPI00017BA153
UniProtKB Acc B4EFY4
UniProtKB ID B4EFY4_BURCJ
UniRef100 UniRef100_B4EFY4
UniRef50 UniRef50_Q1BPZ6
UniRef90 UniRef90_Q399M3

Product

Feature Type CDS
Coding Frame 1
Product Name
putative macrolide-specific ABC-type efflux carrier protein
Synonyms
Evidence for Translation
Charge (pH 7) 6.72
Kyte-Doolittle Hydrophobicity Value 0.141
Molecular Weight (kDa) 73046.3
Isoelectric Point (pI) 8.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000213 (849 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2187
Search term: macB

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:46]
E-value: 1.0e-16
Percent Identity: 30.9

References

No references are associated with this feature.