Burkholderia cenocepacia J2315, BCAM0011 (tdh)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0011
NCBI Locus TagQU43_RS54455
Name
tdh
Replicon chromosome 2
Genomic location 12492 - 13520 (+ strand)

Cross-References

RefSeq WP_006480187.1
GI 206561881
Entrez 6930518
GI 206561881
INSDC CAR53866.1
NCBI Locus Tag QU43_RS54455
NCBI Old Locus Tag BCAM0011
RefSeq WP_006480187.1,GeneID
UniParc UPI00006DA732
UniProtKB Acc B4EFZ7
UniProtKB ID TDH_BURCJ
UniRef100 UniRef100_B4EFZ7
UniRef50 UniRef50_Q9RTU4
UniRef90 UniRef90_Q2T9E1

Product

Feature Type CDS
Coding Frame 1
Product Name
L-threonine 3-dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -2.50
Kyte-Doolittle Hydrophobicity Value 0.051
Molecular Weight (kDa) 37385.9
Isoelectric Point (pI) 6.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5KIA OXIDOREDUCTASE 06/16/16 Crystal structure of L-threonine 3-dehydrogenase from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS (STRAIN ATCC 700388 / DSM 13276 / CIP 106301 / E264) 2.1 X-RAY DIFFRACTION 97.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 561 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004425 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0011
Search term: tdh

Human Homologs

Ensembl 97, assembly GRCh38.p12
sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184]
E-value: 3.0e-36
Percent Identity: 27.0

References

No references are associated with this feature.