Burkholderia cenocepacia J2315, BCAL2455 (parE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2455
NCBI Locus TagQU43_RS48945
Name
parE
Replicon chromosome 1
Genomic location 2720784 - 2722766 (- strand)

Cross-References

RefSeq WP_006487633.1
GI 206560814
Entrez 6933929
GI 206560814
INSDC CAR52756.1
NCBI Locus Tag QU43_RS48945
NCBI Old Locus Tag BCAL2455
RefSeq WP_006487633.1,GeneID
UniParc UPI00017B9927
UniProtKB Acc B4E6I1
UniProtKB ID B4E6I1_BURCJ
UniRef100 UniRef100_B4E6I1
UniRef50 UniRef50_F2BFE8
UniRef90 UniRef90_C5AB90

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA topoisomerase IV subunit B
Synonyms
Evidence for Translation
Charge (pH 7) -8.64
Kyte-Doolittle Hydrophobicity Value -0.356
Molecular Weight (kDa) 72669.1
Isoelectric Point (pI) 5.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 633 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002240 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2455
Search term: parE

Human Homologs

Ensembl 97, assembly GRCh38.p12
DNA topoisomerase II beta [Source:HGNC Symbol;Acc:HGNC:11990]
E-value: 4.0e-29
Percent Identity: 23.4
Ensembl 97, assembly GRCh38.p12
DNA topoisomerase II beta [Source:HGNC Symbol;Acc:HGNC:11990]
E-value: 4.0e-29
Percent Identity: 23.4
Ensembl 97, assembly GRCh38.p12
DNA topoisomerase II beta [Source:HGNC Symbol;Acc:HGNC:11990]
E-value: 4.0e-29
Percent Identity: 23.4

References

No references are associated with this feature.