Burkholderia cenocepacia J2315, BCAL1947 (ecfG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL1947
NCBI Locus TagQU43_RS46280
Name
ecfG
Replicon chromosome 1
Genomic location 2145818 - 2146459 (- strand)

Cross-References

RefSeq WP_012492670.1
GI 206560311
Entrez 6932132
GI 206560311
INSDC CAR52248.1
NCBI Locus Tag QU43_RS46280
NCBI Old Locus Tag BCAL1947
RefSeq WP_012492670.1,GeneID
UniParc UPI00017B9257
UniProtKB Acc B4EBH5
UniProtKB ID B4EBH5_BURCJ
UniRef100 UniRef100_B4EBH5
UniRef50 UniRef50_A2VXQ9
UniRef90 UniRef90_A2VXQ9

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma factor
Product Name Confidence: Class 2
Synonyms sigma factor 70 EcfG
Evidence for Translation
Charge (pH 7) -5.10
Kyte-Doolittle Hydrophobicity Value -0.315
Molecular Weight (kDa) 23223.9
Isoelectric Point (pI) 5.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 464 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001709 (612 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1947
Search term: ecfG

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948