Burkholderia cenocepacia J2315, BCAL1003 (lepA2)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1003
NCBI Locus Tag	QU43_RS41580
Name	lepA2
Replicon	chromosome 1
Genomic location	1089631 - 1091424 (+ strand)

Cross-References

RefSeq	WP_006490871.1
GI	206559396
Entrez	6931377
GI	206559396
NCBI Locus Tag	QU43_RS41580
NCBI Old Locus Tag	BCAL1003
RefSeq	WP_006490871.1,GeneID
UniProtKB Acc	B4EAH5
UniProtKB ID	B4EAH5_BURCJ

Product

Feature Type	CDS
Coding Frame	1
Product Name	GTP-binding protein LepA
Synonyms
Evidence for Translation
Charge (pH 7)	-10.77
Kyte-Doolittle Hydrophobicity Value	-0.127
Molecular Weight (kDa)	65952.3
Isoelectric Point (pI)	5.36

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000973 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1003 Search term: lepA2 Search term: GTP-binding protein LepA

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000281543 GUF1 homolog, GTPase [Source:HGNC Symbol;Acc:HGNC:25799] E-value: 2.0e-168 Percent Identity: 49.0

References