Burkholderia cenocepacia J2315, BCAL0631

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL0631
NCBI Locus Tag	QU43_RS39720
Name
Replicon	chromosome 1
Genomic location	684925 - 685857 (- strand)

Cross-References

RefSeq	WP_006488652.1
GI	206559032
Entrez	6931097
GI	206559032
INSDC	CAR50942.1
NCBI Locus Tag	QU43_RS39720
NCBI Old Locus Tag	BCAL0631
RefSeq	WP_006488652.1,GeneID
UniParc	UPI00017B9105
UniProtKB Acc	B4E955
UniProtKB ID	B4E955_BURCJ
UniRef100	UniRef100_A0A0D1BVK2
UniRef50	UniRef50_H0V797
UniRef90	UniRef90_A4JID6

Product

Feature Type	CDS
Coding Frame	1
Product Name	hydroxymethylglutaryl-CoA lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-4.46
Kyte-Doolittle Hydrophobicity Value	0.157
Molecular Weight (kDa)	32601.8
Isoelectric Point (pI)	5.21

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543 Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 328 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002792 (637 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL0631 Search term: hydroxymethylglutaryl-CoA lyase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000363614 3-hydroxy-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005] E-value: 1.7e-94 Percent Identity: 57.1

References