Burkholderia cenocepacia J2315, BCAL0340

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0340
NCBI Locus TagQU43_RS38235
Name
Synonym: bcsM
Replicon chromosome 1
Genomic location 366232 - 366858 (+ strand)
CommentPart of the T6SS gene cluster

Cross-References

RefSeq WP_012492309.1
GI 206558746
Entrez 6930885
GI 206558746
INSDC CAR50650.1
NCBI Locus Tag QU43_RS38235
NCBI Old Locus Tag BCAL0340
RefSeq WP_012492309.1,GeneID
UniParc UPI00017B90FE
UniProtKB Acc B4E6R2
UniProtKB ID B4E6R2_BURCJ
UniRef100 UniRef100_U1XUC3
UniRef50 UniRef50_Q2SUC7
UniRef90 UniRef90_B1JUN6

Product

Feature Type CDS
Coding Frame 1
Product Name
putative lipoprotein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 6.41
Kyte-Doolittle Hydrophobicity Value -0.268
Molecular Weight (kDa) 21534.1
Isoelectric Point (pI) 10.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 12 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000365 (627 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0340

Human Homologs

References

A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149